The accumulation of exercise and postprandial endothelial function in boys

M. J. Sedgwick, J. G. Morris, M. E. Nevill, L. A. Barrett

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)
    50 Downloads (Pure)


    The purpose of this study was to investigate the effect of accumulating 60min of exercise on endothelial function and triacylglycerol concentrations following the ingestion of a high-fat breakfast and lunch in 14 adolescent boys (aged 12 to 14 years). Two, 2-day main trials (control and exercise) were completed in a counter-balanced, cross-over design. Participants were inactive on day 1 of the control trial but on day 1 of the exercise trial completed 6×10min runs at 70% of peak oxygen uptake, spread over the day. On day 2, triacylglycerol concentrations and flow-mediated dilation (FMD) were measured prior to, and following, ingestion of the high-fat meals. In the control trial, FMD was reduced by 30% and 33% (P<0.001) following the high-fat breakfast and lunch; following exercise these reductions were negated (main effect trial, P=0.002, interaction effect trial × time, P<0.001). The total and incremental areas under the triacylglycerol concentration vs time curve were reduced by 11% and 16% in the exercise trial; however, these differences were not significant (P>0.05). These results support the concept of accumulating physical activity for health in adolescents as the accumulated exercise attenuated the decline in FMD seen following the consumption of high-fat meals.

    Original languageEnglish
    Pages (from-to)e11-e19
    Number of pages8
    JournalScandinavian Journal of Medicine and Science in Sports
    Issue number1
    Publication statusPublished - Feb 2014


    • Cardiovascular disease risk
    • Flow-mediated dilation
    • Postprandial lipemia
    • Triacylglycerol


    Dive into the research topics of 'The accumulation of exercise and postprandial endothelial function in boys'. Together they form a unique fingerprint.

    Cite this