Light and electron microscopical localisation of 5-HT-immunoreactive boutons in the rat trigeminal motor nucleus

Sikha Saha; Kwabena Appenteng; Trevor F C Batten

doi:10.1016/0006-8993(91)90297-9

Light and electron microscopical localisation of 5-HT-immunoreactive boutons in the rat trigeminal motor nucleus

Sikha Saha, Kwabena Appenteng, Trevor F C Batten

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

We have used pre-embedding EM immunohistochemical methods to obtain quantitative data on the frequency and post-synaptic targets of 5-hydroxytryptamine-immunoreactive (5-HT-IR) boutons within the rat V motor nucleus. Thirteen percent (69/531) of all synaptic contacts in the motor nucleus involved 5-HT-IR boutons. Seventy-four percent of 5-HT-IR boutons made axo-dendritic contacts, 20% axo-somatic contacts, and 6% axo-axonic contacts. We conclude that a significant fraction of boutons in the motor nucleus are 5-HT-IR and most contribute to postsynaptic rather than presynaptic effects on trigeminal motoneurones.

Original language	English
Pages (from-to)	145-148
Number of pages	4
Journal	Brain Research
Volume	559
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(91)90297-9
Publication status	Published - 13 Sept 1991
Externally published	Yes

Keywords

Electron microscopy
Motoneuron
Serotonin
Synapse
Trigeminal

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abstract = "We have used pre-embedding EM immunohistochemical methods to obtain quantitative data on the frequency and post-synaptic targets of 5-hydroxytryptamine-immunoreactive (5-HT-IR) boutons within the rat V motor nucleus. Thirteen percent (69/531) of all synaptic contacts in the motor nucleus involved 5-HT-IR boutons. Seventy-four percent of 5-HT-IR boutons made axo-dendritic contacts, 20% axo-somatic contacts, and 6% axo-axonic contacts. We conclude that a significant fraction of boutons in the motor nucleus are 5-HT-IR and most contribute to postsynaptic rather than presynaptic effects on trigeminal motoneurones.",

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AU - Batten, Trevor F C

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AB - We have used pre-embedding EM immunohistochemical methods to obtain quantitative data on the frequency and post-synaptic targets of 5-hydroxytryptamine-immunoreactive (5-HT-IR) boutons within the rat V motor nucleus. Thirteen percent (69/531) of all synaptic contacts in the motor nucleus involved 5-HT-IR boutons. Seventy-four percent of 5-HT-IR boutons made axo-dendritic contacts, 20% axo-somatic contacts, and 6% axo-axonic contacts. We conclude that a significant fraction of boutons in the motor nucleus are 5-HT-IR and most contribute to postsynaptic rather than presynaptic effects on trigeminal motoneurones.

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KW - Serotonin

KW - Synapse

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Light and electron microscopical localisation of 5-HT-immunoreactive boutons in the rat trigeminal motor nucleus

Abstract

Keywords

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