Light and electron microscopical localisation of 5-HT-immunoreactive boutons in the rat trigeminal motor nucleus

Sikha Saha, Kwabena Appenteng, Trevor F C Batten

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

We have used pre-embedding EM immunohistochemical methods to obtain quantitative data on the frequency and post-synaptic targets of 5-hydroxytryptamine-immunoreactive (5-HT-IR) boutons within the rat V motor nucleus. Thirteen percent (69/531) of all synaptic contacts in the motor nucleus involved 5-HT-IR boutons. Seventy-four percent of 5-HT-IR boutons made axo-dendritic contacts, 20% axo-somatic contacts, and 6% axo-axonic contacts. We conclude that a significant fraction of boutons in the motor nucleus are 5-HT-IR and most contribute to postsynaptic rather than presynaptic effects on trigeminal motoneurones.
Original languageEnglish
Pages (from-to)145-148
Number of pages4
JournalBrain Research
Volume559
Issue number1
DOIs
Publication statusPublished - 13 Sep 1991
Externally publishedYes

Keywords

  • Electron microscopy
  • Motoneuron
  • Serotonin
  • Synapse
  • Trigeminal

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