Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy

Lee Ingle, Alan S. Rigby, Sean Carroll, Ron Butterly, Rod F. King, Carlton B. Cooke, John G J F Cleland, Andrew L. Clark

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)
    81 Downloads (Pure)

    Abstract

    Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased body fat. The present study investigated 12-month changes in body composition in patients with LVSD initiated on beta-blocker therapy. Methods: The relation between beta-blocker use and body composition was evaluated in 91 patients (75% male) with LVSD. Body composition was assessed by bioelectrical impedance. Results: Seventeen patients died during the study period. There was no statistical difference among beta-blocker usage, beta-blocker type, or changes in body fat, basal metabolic rate, impedance, fat-free mass, fat mass and total body water. There were no significant differences between any of these measures and beta-blocker usage. Conclusion: After 12 months, changes in body composition were not found to be influenced by initiation of beta-blocker therapy in patients with LVSD.

    Original languageEnglish
    Pages (from-to)46-47
    Number of pages2
    JournalExperimental and Clinical Cardiology
    Volume12
    Issue number1
    Publication statusPublished - 2007

    Keywords

    • Body fat
    • Chronic heart failure
    • Fat mass
    • Fat-free mass

    Fingerprint

    Dive into the research topics of 'Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy'. Together they form a unique fingerprint.

    Cite this